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Featured Publications

SARS-CoV-2 virion

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

HIV-1 Matrix

Maturation of the matrix and viral membrane of HIV-1

Measles virus

Promotion of virus assembly and organization by the measles virus matrix protein

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Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants

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Structural analysis of virus assembly by cryo-electron tomography: Measles virus and respiratory syncytial virus

Digital image of orange colored surface proteins of a virus.

Selected Publications

Image of surface proteins fluorescing various colors.

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

Z Ke, J Oton, K Qu, M Cortese, V Zila, L McKeane, T Nakane, J Zivanov, CJ Neufeldt, B Cerikan, JM Lu…
Nature 588 (7838), 498-502, 2020

Image of surface proteins fluorescing various colors.

Maturation of the matrix and viral membrane of HIV-1

K Qu, Z Ke, V Zila, M Anders-Össwein, B Glass, F Mücksch, R Müller, C Schultz, B Müller, HG Kräusslich…
Science 373 (6555), 700-704, 2021

Image of surface proteins fluorescing various colors.

Promotion of virus assembly and organization by the measles virus matrix protein

Z Ke, JD Strauss, CM Hampton, MA Brindley, RS Dillard, F Leon, KM Lamb, RK Plemper, ER Wright
Nature Communications 9 (1), 1736, 2018

Image of surface proteins fluorescing various colors.

The morphology and assembly of respiratory syncytial virus revealed by cryo-electron tomography

Z Ke, RS Dillard, T Chirkova, F Leon, CC Stobart, CM Hampton, JD Strauss, D Rajan, CA Rostad, JV Taylor…
Viruses 10 (8), 446, 2018

Image of surface proteins fluorescing various colors.

Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells

CM Hampton, JD Strauss, Z Ke, RS Dillard… Nature Protocols. 12(1):150-167 (2017).

Image of surface proteins fluorescing various colors.

A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0

J Zivanov, J Otón, Z Ke, A von Kügelgen, E Pyle, K Qu, D Morado, D Castaño-Díez, G Zanetti, TAM Bharat…
Elife 11, e83724, 2022

Image of surface proteins fluorescing various colors.

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants

Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, ...
BioRxiv, 2023

Image of surface proteins fluorescing various colors.

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

CC Stobart, CA Rostad, Z Ke, RS Dillard, CM Hampton… - Nature Communications, 2016

Image of surface proteins fluorescing various colors.

Obstruction of pilus retraction stimulates bacterial surface sensing

CK Ellison, J Kan, RS Dillard, DT Kysela, A Ducret, C Berne, CM Hampton, Z Ke, ER Wright, N Biais, AB Dalia…
Science 358 (6362), 535-538, 2017

Image of surface proteins fluorescing various colors.

A thermostable, closed SARS-CoV-2 spike protein trimer

X Xiong, K Qu, KA Ciazynska, M Hosmillo, AP Carter, S Ebrahimi, Z Ke, SHW Scheres, L Bergamaschi…
Nature Structural & Molecular Biology 27 (10), 934-941, 2020

Image of surface proteins fluorescing various colors.

A stable immature lattice packages IP6 for HIV capsid maturation

DL Mallery, AB Kleinpeter, N Renner, KMR Faysal, M Novikova, L Kiss, MSC Wilson, B Ahsan, Z Ke…
Science advances 7 (11), eabe4716, 2021

Image of surface proteins fluorescing various colors.

Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core

AJ Pak, A Yu, Z Ke, JAG Briggs, GA Voth
Nature communications 13 (1), 1002, 2022

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